A broad category of small proteins that are important in cell signaling, specifically in the context of the immune system's response to infection, injury, or toxins. Cytokines can be pro-inflammatory or anti-inflammatory, and their balance is crucial for maintaining health. Pro-inflammatory cytokines, such as TNF-alpha and IL-6, are often elevated in individuals with excess adipose tissue, contributing to a state of chronic low-grade inflammation.
These signaling molecules act as messengers that can alter the behavior of distant cells, including those involved in metabolism and hormone regulation. High levels of pro-inflammatory cytokines can lead to insulin resistance and the suppression of adiponectin. Detoxification and nutritional protocols aim to lower the production of these harmful cytokines while promoting the release of anti-inflammatory signals, thereby creating a cellular environment conducive to healing and fat oxidation.
The definitive guide by Russell Clark, FNP-C, APRN