Ketones, or ketone bodies, are water-soluble molecules produced by the liver from fatty acids during periods of low carbohydrate intake, fasting, or prolonged intense exercise. They serve as an alternative energy source for the body, particularly the brain, which cannot directly utilize fatty acids for fuel. The state of elevated circulating ketones is known as ketosis, a metabolic state associated with enhanced fat burning and improved cognitive clarity.
The production of ketones is a hallmark of efficient fat oxidation. In weight loss protocols, shifting the body into a state where it can readily produce and utilize ketones is often a primary objective. This metabolic shift not only facilitates the breakdown of stored adipose tissue but also provides a stable energy source that prevents the crashes associated with glucose metabolism. Furthermore, ketones have signaling properties that can help reduce inflammation and protect against oxidative stress, contributing to overall longevity and metabolic resilience.
The definitive guide by Russell Clark, FNP-C, APRN