Lectins are a diverse family of carbohydrate-binding proteins found in many plant foods, particularly legumes, grains, and certain vegetables like nightshades. In nature, they serve as a defense mechanism for plants against pests. In human nutrition, some theories suggest that high intake of certain lectins can lead to intestinal permeability (leaky gut), systemic inflammation, and interference with nutrient absorption.
A lectin-free or low-lectin diet is often employed in metabolic protocols to reduce potential triggers for autoimmune responses and gut irritation. By eliminating high-lectin foods, proponents argue that individuals can lower systemic inflammation, which in turn improves hormonal signaling and makes weight loss more efficient by removing 'biological friction' caused by food sensitivities.
The definitive guide by Russell Clark, FNP-C, APRN