A colloquial and descriptive term used to define a state of systemic physiological dysfunction where multiple metabolic pathways are impaired simultaneously. This typically includes a combination of insulin resistance, chronic inflammation, hormonal imbalances (such as elevated cortisol and suppressed leptin), and dyslipidemia (high triglycerides and low HDL).
Metabolic chaos often manifests as persistent fatigue, inability to lose weight despite caloric restriction, brain fog, and poor sleep. It is the result of long-term exposure to processed foods, chronic stress, and environmental toxins. Resolving metabolic chaos requires a comprehensive approach that addresses the root causes of hormonal dysregulation rather than just treating individual symptoms.
The definitive guide by Russell Clark, FNP-C, APRN